Monitoring carboplatin ototoxicity with distortion-product otoacoustic emissions in children with retinoblastoma
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چکیده
منابع مشابه
Distortion-product otoacoustic emission test performance for ototoxicity monitoring.
INTRODUCTION A nonbehavioral method for monitoring ototoxicity in patients treated with cisplatin is needed because patients enduring chemotherapy may not be well or cooperative enough to undergo repeated hearing tests. Distortion-product otoacoustic emissions (DPOAEs) provide a nonbehavioral measure of auditory function that is sensitive to cisplatin exposure. However, interpreting DPOAE findi...
متن کاملAccuracy of distortion-product otoacoustic emissions-based ototoxicity monitoring using various primary frequency step-sizes.
OBJECTIVE A cisplatin ototoxicity monitoring protocol was recently proposed using distortion-product otoacoustic emissions (DPOAEs) measured in 1/48th octave steps over the highest obtainable quarter octave ( Dille et al, 2010 ). This protocol can take up to 40 minutes to complete in both ears among seriously ill patients in a potentially noisy test environment. The goal of the current study wa...
متن کاملOtotoxicity risk assessment combining distortion product otoacoustic emissions with a cisplatin dose model.
An objective method for identifying ototoxic hearing loss among patients receiving cisplatin is necessary since the ability of patients to take a behavioral test may change over the course of treatment. Data from 56 monitoring visits by 19 Veterans taking cisplatin were used to identify combinations of distortion-product otoacoustic emission (DPOAE) metrics and ototoxicity risk factors that bes...
متن کاملDistortion product otoacoustic emissions in tinnitus patients.
Tinnitus is a symptom that affects a great number of patients. Its diagnosis, treatment, and follow-up are difficult, owing to its subjectivity. The authors propose the use of distortion product otoacoustic emissions (DPOAEs) in tinnitus evaluation. They studied three groups: controls, having no complaint of tinnitus and normal hearing; group 1, presenting tinnitus and normal audiometry; and gr...
متن کاملVariation of distortion product otoacoustic emissions with furosemide injection.
Cochlear function was monitored in adult gerbils using distortion product otoacoustic emissions (DPOAE) during intraperitoneal injection of furosemide. All stimulus parameters were varied independently over a wide range, the stimulus frequencies f1 and f2 from 1 to 16 kHz, and the stimulus levels L1 and L2 from 20 to 80 dB SPL. The observed emissions at 2f1-f2 and 3f1-2f2 could be considered to...
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ژورنال
عنوان ژورنال: International Journal of Pediatric Otorhinolaryngology
سال: 2010
ISSN: 0165-5876
DOI: 10.1016/j.ijporl.2010.07.004